What is liver tumour treatment?
Liver tumour treatment involves various approaches depending on the type, size and the patient's health. Frequent analysis for liver tumours includes the following:
1. Surgery: surgical removal of the tumour or, in more severe cases, a liver transplant.
2. Ablation Therapy: Using radiofrequency ablation (RFA) or microwave ablation to destroy cancerous cells.
3. Chemoembolisation: directly delivering chemotherapy drugs to the tumour site by blocking the blood supply.
4. Targeted therapy: medications that target specific molecules involved in cancer growth.
5. Immunotherapy: Enhancing the body's immune system to attack cancer cells.
6. Radiation Therapy: Using high doses of radiation to kill or shrink tumours.
7. Chemotherapy: Administering drugs to kill cancer cells or inhibit their growth.
The treatment depends on factors like the type and stage of the liver tumour, the patient's overall health, and the extent of liver function. A multidisciplinary approach involving oncologists, surgeons, and other specialists is often employed to determine the most effective treatment plan for an individual with a liver tumour.
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| Advancements in Liver Tumor Therapies |
What is microsphere therapy for liver tumours?
Microsphere therapy for liver tumours, also known as transarterial radioembolisation (TARE) or selective internal radiation therapy (SIRT), is a minimally invasive procedure used to treat certain types of liver cancers, particularly primary liver cancer (hepatocellular carcinoma) or metastatic liver tumours.
In this therapy, tiny radioactive beads, or microspheres, are delivered directly to the blood vessels that supply the tumour within the liver. Surgeons load these microspheres with a radioactive substance, typically yttrium-90. Once in place, they emit radiation locally, targeting and damaging the cancerous cells while sparing the surrounding healthy liver tissue.
Microsphere therapy serves a dual purpose because it blocks the blood supply to the tumour and delivers a targeted radiation dose to the cancer cells. This approach helps reduce the size of the tumour and control its growth. It is often a consideration in cases where surgery is not a viable option or forms part of a comprehensive treatment plan.
Medical professionals typically assess the patient's overall health, the size and location of the tumour, and other factors to determine if microsphere therapy is a suitable option. It is vital for individuals considering this treatment to consult with their healthcare team to understand the potential benefits and risks associated with the procedure.
What is transarterial radioembolisation (TARE)?
Transarterial radioembolisation, or (TARE) is a unique form of therapy for liver tumours, particularly hepatocellular carcinoma (primary liver cancer) or metastatic liver tumours. This minimally invasive procedure involves the targeted delivery of radioactive microspheres directly to the blood vessels supplying the tumour within the liver.
Vital features of transarterial radioembolisation (TARE) include:
1. Minimally Invasive: TARE is a less-invasive alternative to traditional surgery. Surgeons perform it through a catheter, usually inserted into the groin area and threaded through the blood vessels to the hepatic artery, which supplies blood to the liver.
2. Radiation Delivery: Surgeons load the microspheres in TARE with a radioactive substance, often yttrium-90. Once positioned within the blood vessels feeding the tumour, these microspheres emit bounded radiation, precisely targeting the cancerous cells.
3. Dual Action: TARE acts as an internal radiation therapy to block the blood supply to the tumour. Delivering a concentrated dose of radiation directly to the cancer cells helps to shrink or control the growth of the tumour.
4. Preservation of Healthy Tissue: One advantage of TARE is its ability to control damage to the surrounding healthy liver tissue. The targeted nature of the treatment reduces the impact on non-cancerous cells.
5. Suitability: Surgeons consider TARE in cases where surgery is not a feasible option due to factors such as the size or location of the tumour or when a patient is not a candidate for other treatments.
It's important for individuals considering transarterial radioembolisation to undergo a thorough evaluation by their healthcare team. Deciding to pursue this treatment relies on factors such as the type and stage of the liver tumour, overall health, and the specific characteristics of cancer. Patients should engage in detailed discussions with their medical professionals to understand the potential benefits and risks.
What complications may arise after transarterial radioembolisation (TARE)?
Complications that may arise after transarterial radioembolisation (TARE) include:
1. Post-Embolisation Syndrome: This can cause symptoms such as fatigue, pain, nausea, and fever. It is a common and usually temporary reaction to the treatment.
2. Liver Function Changes: TARE may temporarily affect liver function, leading to elevated liver enzymes. Doctors implement monitoring and management to address these changes.
3. Radiation-related effects: While aiming the radiation, it might affect nearby healthy tissues, possibly causing inflammation or damage.
4. Biliary Injury: In rare cases, the procedure may cause injury to the bile ducts, leading to complications such as bile leakage or strictures.
5. Gastrointestinal Ulcers: The radiation effect on nearby tissues may, in rare instances, result in ulcers in the gastrointestinal tract.
6. Infection: Though uncommon, there is a risk of infection if there is any breach in the skin during the procedure.
It's crucial to note that complications vary among individuals and that adverse effects by factors such as the patient's overall health, the specific characteristics of the tumour, and the medical team performing the procedure. Patients considering TARE should engage in detailed discussions with their doctors to thoroughly understand the potential risks and benefits associated with the treatment.
What are the diet and precautions after transarterial radioembolisation (TARE)?
After transarterial radioembolisation (TARE), healthcare providers generally advise patients to adhere to specific dietary and lifestyle precautions. Although these recommendations may vary based on individual health conditions, common suggestions include:
1. Hydration: Drink plenty of water to stay hydrated, especially in the first few days after the procedure. Adequate hydration supports the body's recovery process.
2. Rest: Allow yourself sufficient time for rest and recovery. Avoid strenuous physical activities for a period recommended by your healthcare provider.
3. Medication Management: Take prescribed medications as directed by your doctors. These medicines may be used for pain relief or to manage potential side effects.
4. Dietary Considerations:
- Soft Diet: Initially, opt for an easily digestible diet to ease digestion.
- Moderate Meals: Consume small, frequent meals instead of large, heavy ones.
- Avoid Alcohol: Limit or avoid alcohol intake, as it can strain the liver.
5. Temperature Monitoring: Keep an eye on your body temperature. If you experience a persistent fever, inform your healthcare provider promptly.
6. Follow-up Appointments: Attend all scheduled follow-up appointments with your healthcare team. Regular monitoring is crucial to assess your recovery and address any concerns.
7. Report Symptoms: Promptly report any unusual symptoms, such as persistent pain, changes in appetite, or signs of infection, to your healthcare provider.
Note that these guidelines are general recommendations and personalised instructions may be given depending on your health status and the specifics of your TARE procedure. Always consult your healthcare team for advice and to address any questions or concerns you may have regarding post-TARE care.
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